Cargando…

The Crucial Role of Xanthine Oxidase in CKD Progression Associated with Hypercholesterolemia

In the present study, we investigated the effects of xanthine oxidase (XO) inhibition on cholesterol-induced renal dysfunction in chronic kidney disease (CKD) mice, and in low-density lipoprotein (LDL)-treated human kidney proximal tubule epithelial (HK-2) cells. ApoE knockout (KO) mice underwent un...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, You-Jin, Oh, Se-Hyun, Ahn, Ji-Sun, Yook, Ju-Min, Kim, Chan-Duck, Park, Sun-Hee, Cho, Jang-Hee, Kim, Yong-Lim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589966/
https://www.ncbi.nlm.nih.gov/pubmed/33050202
http://dx.doi.org/10.3390/ijms21207444