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The Crucial Role of Xanthine Oxidase in CKD Progression Associated with Hypercholesterolemia

In the present study, we investigated the effects of xanthine oxidase (XO) inhibition on cholesterol-induced renal dysfunction in chronic kidney disease (CKD) mice, and in low-density lipoprotein (LDL)-treated human kidney proximal tubule epithelial (HK-2) cells. ApoE knockout (KO) mice underwent un...

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Detalles Bibliográficos
Autores principales:	Kim, You-Jin, Oh, Se-Hyun, Ahn, Ji-Sun, Yook, Ju-Min, Kim, Chan-Duck, Park, Sun-Hee, Cho, Jang-Hee, Kim, Yong-Lim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589966/ https://www.ncbi.nlm.nih.gov/pubmed/33050202 http://dx.doi.org/10.3390/ijms21207444

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