In Vivo Remodeling of Altered Autophagy-Lysosomal Pathway by a Phosphopeptide in Lupus

The phosphopeptide P140/Lupuzor, which improves the course of lupus disease in mice and patients, targets chaperone-mediated autophagy (CMA), a selective form of autophagy that is abnormally upregulated in lupus-prone MRL/lpr mice. Administered intravenously to diseased mice, P140 reduces the expres...

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Detalles Bibliográficos
Autores principales: Wang, Fengjuan, Tasset, Inmaculada, Cuervo, Ana Maria, Muller, Sylviane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589999/
https://www.ncbi.nlm.nih.gov/pubmed/33092174
http://dx.doi.org/10.3390/cells9102328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7589999/
https://www.ncbi.nlm.nih.gov/pubmed/33092174
http://dx.doi.org/10.3390/cells9102328

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