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Comparative Study of the Steroidogenic Effects of Human Chorionic Gonadotropin and Thieno[2,3-D]pyrimidine-Based Allosteric Agonist of Luteinizing Hormone Receptor in Young Adult, Aging and Diabetic Male Rats

Low-molecular-weight agonists of luteinizing hormone (LH)/human chorionic gonadotropin (hCG) receptor (LHCGR), which interact with LHCGR transmembrane allosteric site and, in comparison with gonadotropins, more selectively activate intracellular effectors, are currently being developed. Meanwhile, t...

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Detalles Bibliográficos
Autores principales: Bakhtyukov, Andrey A., Derkach, Kira V., Gureev, Maxim A., Dar’in, Dmitry V., Sorokoumov, Viktor N., Romanova, Irina V., Morina, Irina Yu., Stepochkina, Anna M., Shpakov, Alexander O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590010/
https://www.ncbi.nlm.nih.gov/pubmed/33050653
http://dx.doi.org/10.3390/ijms21207493