Toward G-Quadruplex-Based Anticancer Agents: Biophysical and Biological Studies of Novel AS1411 Derivatives

Certain G-quadruplex forming guanine-rich oligonucleotides (GROs), including AS1411, are endowed with cancer-selective antiproliferative activity. They are known to bind to nucleolin protein, resulting in the inhibition of nucleolin-mediated phenomena. However, multiple nucleolin-independent biologi...

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Detalles Bibliográficos
Autores principales: Ogloblina, Anna M., Iaccarino, Nunzia, Capasso, Domenica, Di Gaetano, Sonia, Garzarella, Emanuele U., Dolinnaya, Nina G., Yakubovskaya, Marianna G., Pagano, Bruno, Amato, Jussara, Randazzo, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590035/
https://www.ncbi.nlm.nih.gov/pubmed/33096752
http://dx.doi.org/10.3390/ijms21207781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590035/
https://www.ncbi.nlm.nih.gov/pubmed/33096752
http://dx.doi.org/10.3390/ijms21207781

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