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One‐Pot Synthesis of Chiral N‐Arylamines by Combining Biocatalytic Aminations with Buchwald–Hartwig N‐Arylation

The combination of biocatalysis and chemo‐catalysis increasingly offers chemists access to more diverse chemical architectures. Here, we describe the combination of a toolbox of chiral‐amine‐producing biocatalysts with a Buchwald–Hartwig cross‐coupling reaction, affording a variety of α‐chiral anili...

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Detalles Bibliográficos
Autores principales: Cosgrove, Sebastian C., Thompson, Matthew P., Ahmed, Syed T., Parmeggiani, Fabio, Turner, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590080/
https://www.ncbi.nlm.nih.gov/pubmed/32628797
http://dx.doi.org/10.1002/anie.202006246