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Validation of a prostate cancer polygenic risk score

BACKGROUND: Genome‐wide association studies have identified over 100 single‐nucleotide polymorphisms (SNPs) associated with prostate cancer (PrCa), and polygenic risk scores (PRS) based on their combined genotypes have been developed for risk stratification. We aimed to assess the contribution of PR...

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Detalles Bibliográficos
Autores principales: Black, Mary H., Li, Shuwei, LaDuca, Holly, Lo, Min‐Tzu, Chen, Jefferey, Hoiness, Robert, Gutierrez, Stephanie, Tippin‐Davis, Brigette, Lu, Hsiao‐Mei, Gielzak, Marta, Wiley, Kathleen, Shi, Zhuqing, Wei, Jun, Zheng, Siqun Lilly, Helfand, Brian T., Isaacs, William, Xu, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590110/
https://www.ncbi.nlm.nih.gov/pubmed/33258481
http://dx.doi.org/10.1002/pros.24058