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Synthesis of Highly Enantioenriched Sulfonimidoyl Fluorides and Sulfonimidamides by Stereospecific Sulfur–Fluorine Exchange (SuFEx) Reaction

Sulfonimidamides present exciting opportunities as chiral isosteres of sulfonamides, with potential for additional directional interactions. Here, we present the first modular enantioselective synthesis of sulfonimidamides, including the first stereoselective synthesis of enantioenriched sulfonimido...

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Detalles Bibliográficos
Autores principales: Greed, Stephanie, Briggs, Edward L., Idiris, Fahima I. M., White, Andrew J. P., Lücking, Ulrich, Bull, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590120/
https://www.ncbi.nlm.nih.gov/pubmed/32428384
http://dx.doi.org/10.1002/chem.202002265