Specific Effects of Trabectedin and Lurbinectedin on Human Macrophage Function and Fate—Novel Insights

SIMPLE SUMMARY: Trabectedin and lurbinectedin are two potent onco-therapeutic drugs for the treatment of advanced soft tissue sarcomas. Here we show that, in addition to cancer cells, these molecules exert important effects on macrophages and tissue-associated macrophages altering metabolic function...

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Detalles Bibliográficos
Autores principales: Povo-Retana, Adrián, Mojena, Marina, Stremtan, Adrian B., Fernández-García, Victoria B., Gómez-Sáez, Ana, Nuevo-Tapioles, Cristina, Molina-Guijarro, José M., Avendaño-Ortiz, José, Cuezva, José M., López-Collazo, Eduardo, Martínez-Leal, Juan F., Boscá, Lisardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590144/
https://www.ncbi.nlm.nih.gov/pubmed/33092171
http://dx.doi.org/10.3390/cancers12103060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590144/
https://www.ncbi.nlm.nih.gov/pubmed/33092171
http://dx.doi.org/10.3390/cancers12103060

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