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The Signaling Duo CXCL12 and CXCR4: Chemokine Fuel for Breast Cancer Tumorigenesis

SIMPLE SUMMARY: Breast cancer remains the most common malignancy in women. In this review, we explore the role of the CXCL12/CXCR4 pathway in breast cancer. We show that the CXCL12/CXCR4 cascade is involved in nearly every aspect of breast cancer tumorigenesis including proliferation, cell motility...

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Detalles Bibliográficos
Autores principales: Zielińska, Karolina A., Katanaev, Vladimir L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590182/
https://www.ncbi.nlm.nih.gov/pubmed/33096815
http://dx.doi.org/10.3390/cancers12103071