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Aptamers with Tunable Affinity Enable Single‐Molecule Tracking and Localization of Membrane Receptors on Living Cancer Cells

Tumor cell‐surface markers are usually overexpressed or mutated protein receptors for which spatiotemporal regulation differs between and within cancers. Single‐molecule fluorescence imaging can profile individual markers in different cellular contexts with molecular precision. However, standard sin...

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Detalles Bibliográficos
Autores principales: Delcanale, Pietro, Porciani, David, Pujals, Silvia, Jurkevich, Alexander, Chetrusca, Andrian, Tawiah, Kwaku D., Burke, Donald H., Albertazzi, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590183/
https://www.ncbi.nlm.nih.gov/pubmed/32627326
http://dx.doi.org/10.1002/anie.202004764