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Allogeneic adipose‐derived stem cells promote ischemic muscle repair by inducing M2 macrophage polarization via the HIF‐1α/IL‐10 pathway

Adipose‐derived mesenchymal stem cells (ASCs) are multipotent stromal cells that possess considerable therapeutic potential for tissue remodeling. However, their protective mechanism in critical limb ischemia has not been fully defined. After the occlusion of blood vessels, hypoxia becomes a promine...

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Detalles Bibliográficos
Autores principales: Liu, Junchao, Qiu, Peng, Qin, Jinbao, Wu, Xiaoyu, Wang, Xin, Yang, Xinrui, Li, Bo, Zhang, Wenjie, Ye, Kaichuang, Peng, Zhiyou, Lu, Xinwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590195/
https://www.ncbi.nlm.nih.gov/pubmed/32627897
http://dx.doi.org/10.1002/stem.3250