Symptomatic COVID-19 infections in outpatient image-guided corticosteroid injection patients during the lockdown phase

BACKGROUND: Musculoskeletal pain is a debilitating problem treated with image-guided corticosteroid injections. During the COVID-19 pandemic, multiple societies issued caution statements because of the unknown effect of corticosteroids on the patient’s immune system. The purpose is to determine if i...

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Autores principales: Chang, Connie Y., Prabhakar, Anand, Staffa, Steven J., Husseini, Jad S., Kheterpal, Arvin B., Simeone, F. Joseph, Bredella, Miriam A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590247/
https://www.ncbi.nlm.nih.gov/pubmed/33108512
http://dx.doi.org/10.1007/s00256-020-03656-w
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author Chang, Connie Y.
Prabhakar, Anand
Staffa, Steven J.
Husseini, Jad S.
Kheterpal, Arvin B.
Simeone, F. Joseph
Bredella, Miriam A.
author_facet Chang, Connie Y.
Prabhakar, Anand
Staffa, Steven J.
Husseini, Jad S.
Kheterpal, Arvin B.
Simeone, F. Joseph
Bredella, Miriam A.
author_sort Chang, Connie Y.
collection PubMed
description BACKGROUND: Musculoskeletal pain is a debilitating problem treated with image-guided corticosteroid injections. During the COVID-19 pandemic, multiple societies issued caution statements because of the unknown effect of corticosteroids on the patient’s immune system. The purpose is to determine if image-guided corticosteroid injections administered during the COVID-19 lockdown phase were associated with a higher infection rate compared to the general population. MATERIALS AND METHODS: In a prospective study, patients undergoing image-guided corticosteroid injections for pain management during the lockdown phase between April 15 and May 22, 2020, were enrolled. One month after the injection, patients were surveyed by telephone for any COVID-19-related symptoms, and the electronic medical record (EMR) was reviewed for symptoms and test results. RESULTS: Seventy-one subjects were recruited, 31 (44%) females, 40 (56%) males, ages 58 ± 17 (20–92) years. Follow-up was available in 66 (93%) of subjects, 60 (91%) by phone survey and EMR, 6 (9%) by EMR only, 45 ± 22 (19–83) days after injection. One (1/66, 1.52%; 95% CI 0.04–8.2%) 25-year-old male subject developed symptomatic infection 19 days after a tibiotalar injection. The prevalence of COVID-19 cases in the state of Massachusetts was 0.91% (62,726/6,892,503) during the study period. There was no significant difference in the rate of occurrence of new cases of COVID-19 infection between the corticosteroid injection group and the general population (p = 0.44). CONCLUSION: Image-guided corticosteroid injections for pain management performed during the lockdown phase of the COVID-19 pandemic were not associated with a higher infection rate compared to the general population.
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spelling pubmed-75902472020-10-27 Symptomatic COVID-19 infections in outpatient image-guided corticosteroid injection patients during the lockdown phase Chang, Connie Y. Prabhakar, Anand Staffa, Steven J. Husseini, Jad S. Kheterpal, Arvin B. Simeone, F. Joseph Bredella, Miriam A. Skeletal Radiol Scientific Article BACKGROUND: Musculoskeletal pain is a debilitating problem treated with image-guided corticosteroid injections. During the COVID-19 pandemic, multiple societies issued caution statements because of the unknown effect of corticosteroids on the patient’s immune system. The purpose is to determine if image-guided corticosteroid injections administered during the COVID-19 lockdown phase were associated with a higher infection rate compared to the general population. MATERIALS AND METHODS: In a prospective study, patients undergoing image-guided corticosteroid injections for pain management during the lockdown phase between April 15 and May 22, 2020, were enrolled. One month after the injection, patients were surveyed by telephone for any COVID-19-related symptoms, and the electronic medical record (EMR) was reviewed for symptoms and test results. RESULTS: Seventy-one subjects were recruited, 31 (44%) females, 40 (56%) males, ages 58 ± 17 (20–92) years. Follow-up was available in 66 (93%) of subjects, 60 (91%) by phone survey and EMR, 6 (9%) by EMR only, 45 ± 22 (19–83) days after injection. One (1/66, 1.52%; 95% CI 0.04–8.2%) 25-year-old male subject developed symptomatic infection 19 days after a tibiotalar injection. The prevalence of COVID-19 cases in the state of Massachusetts was 0.91% (62,726/6,892,503) during the study period. There was no significant difference in the rate of occurrence of new cases of COVID-19 infection between the corticosteroid injection group and the general population (p = 0.44). CONCLUSION: Image-guided corticosteroid injections for pain management performed during the lockdown phase of the COVID-19 pandemic were not associated with a higher infection rate compared to the general population. Springer Berlin Heidelberg 2020-10-27 2021 /pmc/articles/PMC7590247/ /pubmed/33108512 http://dx.doi.org/10.1007/s00256-020-03656-w Text en © ISS 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Scientific Article
Chang, Connie Y.
Prabhakar, Anand
Staffa, Steven J.
Husseini, Jad S.
Kheterpal, Arvin B.
Simeone, F. Joseph
Bredella, Miriam A.
Symptomatic COVID-19 infections in outpatient image-guided corticosteroid injection patients during the lockdown phase
title Symptomatic COVID-19 infections in outpatient image-guided corticosteroid injection patients during the lockdown phase
title_full Symptomatic COVID-19 infections in outpatient image-guided corticosteroid injection patients during the lockdown phase
title_fullStr Symptomatic COVID-19 infections in outpatient image-guided corticosteroid injection patients during the lockdown phase
title_full_unstemmed Symptomatic COVID-19 infections in outpatient image-guided corticosteroid injection patients during the lockdown phase
title_short Symptomatic COVID-19 infections in outpatient image-guided corticosteroid injection patients during the lockdown phase
title_sort symptomatic covid-19 infections in outpatient image-guided corticosteroid injection patients during the lockdown phase
topic Scientific Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590247/
https://www.ncbi.nlm.nih.gov/pubmed/33108512
http://dx.doi.org/10.1007/s00256-020-03656-w
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