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Effects of thrombomodulin alfa on hemostatic parameters in disseminated intravascular coagulation: Post hoc analysis of a phase 3 randomized controlled trial

BACKGROUND: The efficacy and safety of thrombomodulin alfa (TM‐α), a cofactor protein promoting thrombin‐mediated protein C activation, have been examined in a phase 3 randomized, double‐blinded, parallel‐group trial in Japan. We have previously reported that TM‐α is noninferior to heparin for the r...

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Detalles Bibliográficos
Autores principales: Ito, Takashi, Maruyama, Ikuro, Shimazaki, Shuji, Yamamoto, Yasuhiro, Aikawa, Naoki, Hirayama, Akio, Honda, Goichi, Saito, Hidehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590306/
https://www.ncbi.nlm.nih.gov/pubmed/33134780
http://dx.doi.org/10.1002/rth2.12419