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Effects of thrombomodulin alfa on hemostatic parameters in disseminated intravascular coagulation: Post hoc analysis of a phase 3 randomized controlled trial
BACKGROUND: The efficacy and safety of thrombomodulin alfa (TM‐α), a cofactor protein promoting thrombin‐mediated protein C activation, have been examined in a phase 3 randomized, double‐blinded, parallel‐group trial in Japan. We have previously reported that TM‐α is noninferior to heparin for the r...
Autores principales: | Ito, Takashi, Maruyama, Ikuro, Shimazaki, Shuji, Yamamoto, Yasuhiro, Aikawa, Naoki, Hirayama, Akio, Honda, Goichi, Saito, Hidehiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590306/ https://www.ncbi.nlm.nih.gov/pubmed/33134780 http://dx.doi.org/10.1002/rth2.12419 |
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