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Prostasin and hepatocyte growth factor B in factor VIIa generation: Serine protease knockdowns in zebrafish

BACKGROUND: Blood clotting in humans is initiated by the binding of tissue factor to activated coagulation factor VII (FVIIa) in the plasma. Previous studies have reported that hepsin and factor VII (FVII)‐activating protease are responsible for generating FVIIa. OBJECTIVES: We aimed to identify oth...

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Detalles Bibliográficos
Autores principales: Khandekar, Gauri, Iyer, Neha, Jagadeeswaran, Pudur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590325/
https://www.ncbi.nlm.nih.gov/pubmed/33134781
http://dx.doi.org/10.1002/rth2.12428