Cargando…

Multi-transcription factor reporter mice delineate early precursors to the ILC and LTi lineages

Transcription factor (TF) reporter mice have proved integral to the characterization of murine innate lymphoid cell (ILC) development and function. Here, we implemented a CRISPR/Cas9-generated combinatorial reporter approach for the simultaneous resolution of several key TFs throughout ILC developme...

Descripción completa

Detalles Bibliográficos
Autores principales: Kasal, Darshan N., Bendelac, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590509/
https://www.ncbi.nlm.nih.gov/pubmed/33104170
http://dx.doi.org/10.1084/jem.20200487