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Multi-transcription factor reporter mice delineate early precursors to the ILC and LTi lineages
Transcription factor (TF) reporter mice have proved integral to the characterization of murine innate lymphoid cell (ILC) development and function. Here, we implemented a CRISPR/Cas9-generated combinatorial reporter approach for the simultaneous resolution of several key TFs throughout ILC developme...
Autores principales: | Kasal, Darshan N., Bendelac, Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590509/ https://www.ncbi.nlm.nih.gov/pubmed/33104170 http://dx.doi.org/10.1084/jem.20200487 |
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