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The prognostic implications of Notch1, Hes1, Ascl1, and DLL3 protein expression in SCLC patients receiving platinum-based chemotherapy

OBJECTIVES: The aim was to analyse the tumor expression of Notch1, Hes1, Ascl1, and DLL3 in Small-Cell Lung Cancer (SCLC) and each such biomarker’s potential association with clinical characteristics and prognosis after platinum-doublet chemotherapy (PDCT). MATERIAL AND METHODS: The protein expressi...

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Detalles Bibliográficos
Autores principales: Tendler, Salomon, Kanter, Lena, Lewensohn, Rolf, Ortiz-Villalón, Cristian, Viktorsson, Kristina, De Petris, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590528/
https://www.ncbi.nlm.nih.gov/pubmed/33104707
http://dx.doi.org/10.1371/journal.pone.0240973