Mesenchymal stem cell-derived exosomal microRNA-136-5p inhibits chondrocyte degeneration in traumatic osteoarthritis by targeting ELF3

BACKGROUND: Emerging evidence suggests that microRNAs (miRs) are associated with the progression of osteoarthritis (OA). In this study, the role of exosomal miR-136-5p derived from mesenchymal stem cells (MSCs) in OA progression is investigated and the potential therapeutic mechanism explored. METHO...

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Detalles Bibliográficos
Autores principales: Chen, Xue, Shi, Yuanyuan, Xue, Pan, Ma, Xinli, Li, Junfeng, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590698/
https://www.ncbi.nlm.nih.gov/pubmed/33109253
http://dx.doi.org/10.1186/s13075-020-02325-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590698/
https://www.ncbi.nlm.nih.gov/pubmed/33109253
http://dx.doi.org/10.1186/s13075-020-02325-6

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