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Treating primary immunodeficiencies with defects in NK cells: from stem cell therapy to gene editing
Primary immunodeficiency diseases (PIDs) are rare diseases that are characterized by genetic mutations that damage immunological function, defense, or both. Some of these rare diseases are caused by aberrations in the normal development of natural killer cells (NKs) or affect their lytic synapse. Th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590703/ https://www.ncbi.nlm.nih.gov/pubmed/33109263 http://dx.doi.org/10.1186/s13287-020-01964-5 |