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Two-Plasmid Packaging System for Recombinant Adeno-Associated Virus

A number of packaging systems are available for production of recombinant adeno-associated virus vectors (rAAVs). Among these, the use of a two-plasmid cotransfection system, in which Rep and Cap genes and Ad helper genes are on the same plasmid, has not been frequently employed for good manufacturi...

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Detalles Bibliográficos
Autores principales: Tang, Qiushi, Keeler, Allison M., Zhang, Songbo, Su, Qin, Lyu, Zhuoyao, Cheng, Yangfan, Gao, Guangping, Flotte, Terence R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7590824/
https://www.ncbi.nlm.nih.gov/pubmed/33117614
http://dx.doi.org/10.1089/biores.2020.0031