A Rad51-independent pathway promotes single-strand template repair in gene editing

The Rad51/RecA family of recombinases perform a critical function in typical repair of double-strand breaks (DSBs): strand invasion of a resected DSB end into a homologous double-stranded DNA (dsDNA) template sequence to initiate repair. However, repair of a DSB using single stranded DNA (ssDNA) as...

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Detalles Bibliográficos
Autores principales: Gallagher, Danielle N., Pham, Nhung, Tsai, Annie M., Janto, Nicolas V., Choi, Jihyun, Ira, Grzegorz, Haber, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591047/
https://www.ncbi.nlm.nih.gov/pubmed/33057349
http://dx.doi.org/10.1371/journal.pgen.1008689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591047/
https://www.ncbi.nlm.nih.gov/pubmed/33057349
http://dx.doi.org/10.1371/journal.pgen.1008689

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