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Metformin partially reverses the inhibitory effect of co-culture with ER(-)/PR(-)/HER2(+) breast cancer cells on biomarkers of monocyte antitumor activity
BACKGROUND: Immune activities of monocytes (MOs) can be altered within the microenvironment of solid malignancies, including breast cancer. Metformin (1,1-dimethylbiguanide hydrochloride, MET), has been shown to decrease tumor cell proliferation, but its effects have yet to be explored with respect...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591052/ https://www.ncbi.nlm.nih.gov/pubmed/33108409 http://dx.doi.org/10.1371/journal.pone.0240982 |