Metformin partially reverses the inhibitory effect of co-culture with ER(-)/PR(-)/HER2(+) breast cancer cells on biomarkers of monocyte antitumor activity

BACKGROUND: Immune activities of monocytes (MOs) can be altered within the microenvironment of solid malignancies, including breast cancer. Metformin (1,1-dimethylbiguanide hydrochloride, MET), has been shown to decrease tumor cell proliferation, but its effects have yet to be explored with respect...

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Detalles Bibliográficos
Autores principales: Dahmani, Zoheir, Addou-Klouche, Lynda, Gizard, Florence, Dahou, Sara, Messaoud, Aida, Chahinez Djebri, Nihel, Benaissti, Mahmoud Idris, Mostefaoui, Meriem, Terbeche, Hadjer, Nouari, Wafa, Miliani, Marwa, Lefranc, Gérard, Fernandez, Anne, Lamb, Ned J., Aribi, Mourad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591052/
https://www.ncbi.nlm.nih.gov/pubmed/33108409
http://dx.doi.org/10.1371/journal.pone.0240982

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