Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus known to cause epidemics resulting in predominantly symptomatic infections, which in rare cases cause long term debilitating arthritis and arthralgia. Significant progress has been made in understanding the roles of canonical RNA sensing pathw...

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Detalles Bibliográficos
Autores principales: Webb, L. G., Veloz, J., Pintado-Silva, J., Zhu, T., Rangel, M. V., Mutetwa, T., Zhang, L., Bernal-Rubio, D., Figueroa, D., Carrau, L., Fenutria, R., Potla, U., Reid, St. P., Yount, J. S., Stapleford, K. A., Aguirre, S., Fernandez-Sesma, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591055/
https://www.ncbi.nlm.nih.gov/pubmed/33057424
http://dx.doi.org/10.1371/journal.ppat.1008999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591055/
https://www.ncbi.nlm.nih.gov/pubmed/33057424
http://dx.doi.org/10.1371/journal.ppat.1008999

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