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A single Ho-induced double-strand break at the MAT locus is lethal in Candida glabrata

Mating-type switching is a complex mechanism that promotes sexual reproduction in Saccharomycotina. In the model species Saccharomyces cerevisiae, mating-type switching is initiated by the Ho endonuclease that performs a site-specific double-strand break (DSB) at MAT, repaired by homologous recombin...

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Detalles Bibliográficos
Autores principales: Maroc, Laetitia, Zhou-Li, Youfang, Boisnard, Stéphanie, Fairhead, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591073/
https://www.ncbi.nlm.nih.gov/pubmed/33057400
http://dx.doi.org/10.1371/journal.pgen.1008627