MicroRNA-16 Inhibits Glioblastoma Growth in Orthotopic Model by Targeting Cyclin D1 and WIP1

INTRODUCTION: To examine the molecular mechanism by which miRNA-16 (miR-16) suppresses glioblastoma in vitro and in vivo. METHODS: Gene expression of miR-16 in normal brain tissues and human glioma cell lines was examined. To characterize the functional role of miR-16 in vitro, miR-16 was ectopicall...

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Detalles Bibliográficos
Autores principales: Wang, Heng, Pan, Jun, Yu, Lisheng, Meng, Linghu, Liu, Yue, Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591102/
https://www.ncbi.nlm.nih.gov/pubmed/33122919
http://dx.doi.org/10.2147/OTT.S250369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591102/
https://www.ncbi.nlm.nih.gov/pubmed/33122919
http://dx.doi.org/10.2147/OTT.S250369

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