Drivers and sites of diversity in the DNA adenine methylomes of 93 Mycobacterium tuberculosis complex clinical isolates

This study assembles DNA adenine methylomes for 93 Mycobacterium tuberculosis complex (MTBC) isolates from seven lineages paired with fully-annotated, finished, de novo assembled genomes. Integrative analysis yielded four key results. First, methyltransferase allele-methylome mapping corrected methy...

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Detalles Bibliográficos
Autores principales: Modlin, Samuel J, Conkle-Gutierrez, Derek, Kim, Calvin, Mitchell, Scott N, Morrissey, Christopher, Weinrick, Brian C, Jacobs, William R, Ramirez-Busby, Sarah M, Hoffner, Sven E, Valafar, Faramarz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591249/
https://www.ncbi.nlm.nih.gov/pubmed/33107429
http://dx.doi.org/10.7554/eLife.58542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591249/
https://www.ncbi.nlm.nih.gov/pubmed/33107429
http://dx.doi.org/10.7554/eLife.58542

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