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A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain
Microglia are the resident myeloid cells in the central nervous system (CNS). The majority of microglia rely on CSF1R signaling for survival. However, a small subset of microglia in mouse brains can survive without CSF1R signaling and reestablish the microglial homeostatic population after CSF1R sig...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591254/ https://www.ncbi.nlm.nih.gov/pubmed/33054973 http://dx.doi.org/10.7554/eLife.51796 |