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A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain

Microglia are the resident myeloid cells in the central nervous system (CNS). The majority of microglia rely on CSF1R signaling for survival. However, a small subset of microglia in mouse brains can survive without CSF1R signaling and reestablish the microglial homeostatic population after CSF1R sig...

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Detalles Bibliográficos
Autores principales: Zhan, Lihong, Fan, Li, Kodama, Lay, Sohn, Peter Dongmin, Wong, Man Ying, Mousa, Gergey Alzaem, Zhou, Yungui, Li, Yaqiao, Gan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591254/
https://www.ncbi.nlm.nih.gov/pubmed/33054973
http://dx.doi.org/10.7554/eLife.51796