Critical role of WNK1 in MYC-dependent early mouse thymocyte development

WNK1, a kinase that controls kidney salt homeostasis, also regulates adhesion and migration in CD4(+) T cells. Wnk1 is highly expressed in thymocytes, and since migration is important for thymocyte maturation, we investigated a role for WNK1 in mouse thymocyte development. We find that WNK1 is requi...

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Detalles Bibliográficos
Autores principales: Köchl, Robert, Vanes, Lesley, Llorian Sopena, Miriam, Chakravarty, Probir, Hartweger, Harald, Fountain, Kathryn, White, Andrea, Cowan, Jennifer, Anderson, Graham, Tybulewicz, Victor LJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591260/
https://www.ncbi.nlm.nih.gov/pubmed/33051000
http://dx.doi.org/10.7554/eLife.56934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591260/
https://www.ncbi.nlm.nih.gov/pubmed/33051000
http://dx.doi.org/10.7554/eLife.56934

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