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Critical role of WNK1 in MYC-dependent early mouse thymocyte development
WNK1, a kinase that controls kidney salt homeostasis, also regulates adhesion and migration in CD4(+) T cells. Wnk1 is highly expressed in thymocytes, and since migration is important for thymocyte maturation, we investigated a role for WNK1 in mouse thymocyte development. We find that WNK1 is requi...
Autores principales: | Köchl, Robert, Vanes, Lesley, Llorian Sopena, Miriam, Chakravarty, Probir, Hartweger, Harald, Fountain, Kathryn, White, Andrea, Cowan, Jennifer, Anderson, Graham, Tybulewicz, Victor LJ |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591260/ https://www.ncbi.nlm.nih.gov/pubmed/33051000 http://dx.doi.org/10.7554/eLife.56934 |
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