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Duloxetine-Induced Neural Cell Death and Promoted Neurite Outgrowth in N2a Cells
Duloxetine is a clinical drug that is primarily used for treatment of depression and pain, but it has side effects of addiction and tolerance. Cytochrome P450 (CYP) is its metabolic enzyme, and the drug’s biofunction results from its neuro-protective effect in animal and cell models. We aimed to inv...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591439/ https://www.ncbi.nlm.nih.gov/pubmed/32415528 http://dx.doi.org/10.1007/s12640-020-00216-x |