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Duloxetine-Induced Neural Cell Death and Promoted Neurite Outgrowth in N2a Cells

Duloxetine is a clinical drug that is primarily used for treatment of depression and pain, but it has side effects of addiction and tolerance. Cytochrome P450 (CYP) is its metabolic enzyme, and the drug’s biofunction results from its neuro-protective effect in animal and cell models. We aimed to inv...

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Detalles Bibliográficos
Autores principales: Gao, Wanli, Chen, Rui, Xie, Nan, Tang, Daolin, Zhou, Borong, Wang, Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591439/
https://www.ncbi.nlm.nih.gov/pubmed/32415528
http://dx.doi.org/10.1007/s12640-020-00216-x