Modeling early stage atherosclerosis in a primary human vascular microphysiological system

Novel atherosclerosis models are needed to guide clinical therapy. Here, we report an in vitro model of early atherosclerosis by fabricating and perfusing multi-layer arteriole-scale human tissue-engineered blood vessels (TEBVs) by plastic compression. TEBVs maintain mechanical strength, vasoactivit...

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Detalles Bibliográficos
Autores principales: Zhang, Xu, Bishawi, Muath, Zhang, Ge, Prasad, Varun, Salmon, Ellen, Breithaupt, Jason J., Zhang, Qiao, Truskey, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591486/
https://www.ncbi.nlm.nih.gov/pubmed/33110060
http://dx.doi.org/10.1038/s41467-020-19197-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591486/
https://www.ncbi.nlm.nih.gov/pubmed/33110060
http://dx.doi.org/10.1038/s41467-020-19197-8

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