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Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis

Biomarkers are needed for predicting the effectiveness of disease modifying antirheumatic drugs (DMARDs). Here, using functional lipid mediator profiling and deeply phenotyped patients with early rheumatoid arthritis (RA), we observe that peripheral blood  specialized pro-resolving mediator (SPM) co...

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Detalles Bibliográficos
Autores principales: Gomez, Esteban A., Colas, Romain A., Souza, Patricia R., Hands, Rebecca, Lewis, Myles J., Bessant, Conrad, Pitzalis, Costantino, Dalli, Jesmond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591509/
https://www.ncbi.nlm.nih.gov/pubmed/33110080
http://dx.doi.org/10.1038/s41467-020-19176-z