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MiR-155/GSK-3β mediates anti-inflammatory effect of Chikusetsusaponin IVa by inhibiting NF-κB signaling pathway in LPS-induced RAW264.7 cell

It has been demonstrated that Chikusetsusaponin IVa (CsIVa) possesses abundant biological activities. Herein, using LPS to establish acute inflammation model of mouse liver and cell line inflammation model, we investigated whether miR-155/GSK-3β regulated NF-κB signaling pathway, and CsIVa exerted a...

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Detalles Bibliográficos
Autores principales: Xin, Yi, Yuan, Qin, Liu, Chaoqi, Zhang, Changcheng, Yuan, Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591521/
https://www.ncbi.nlm.nih.gov/pubmed/33110183
http://dx.doi.org/10.1038/s41598-020-75358-1