Cyclocreatine treatment ameliorates the cognitive, autistic and epileptic phenotype in a mouse model of Creatine Transporter Deficiency

Creatine Transporter Deficiency (CTD) is an inborn error of metabolism presenting with intellectual disability, behavioral disturbances and epilepsy. There is currently no cure for this disorder. Here, we employed novel biomarkers for monitoring brain function, together with well-established behavio...

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Detalles Bibliográficos
Autores principales: Cacciante, Francesco, Gennaro, Mariangela, Sagona, Giulia, Mazziotti, Raffaele, Lupori, Leonardo, Cerri, Elisa, Putignano, Elena, Butt, Mark, Do, Minh-Ha T., McKew, John C., Alessandrì, Maria Grazia, Battini, Roberta, Cioni, Giovanni, Pizzorusso, Tommaso, Baroncelli, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591530/
https://www.ncbi.nlm.nih.gov/pubmed/33110151
http://dx.doi.org/10.1038/s41598-020-75436-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591530/
https://www.ncbi.nlm.nih.gov/pubmed/33110151
http://dx.doi.org/10.1038/s41598-020-75436-4

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