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Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression

Tumor necrosis commonly exists and predicts poor prognoses in many cancers. Although it is thought to result from chronic ischemia, the underlying nature and mechanisms driving the involved cell death remain obscure. Here, we show that necrosis in glioblastoma (GBM) involves neutrophil-triggered fer...

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Detalles Bibliográficos
Autores principales: Yee, Patricia P., Wei, Yiju, Kim, Soo-Yeon, Lu, Tong, Chih, Stephen Y., Lawson, Cynthia, Tang, Miaolu, Liu, Zhijun, Anderson, Benjamin, Thamburaj, Krishnamoorthy, Young, Megan M., Aregawi, Dawit G., Glantz, Michael J., Zacharia, Brad E., Specht, Charles S., Wang, Hong-Gang, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591536/
https://www.ncbi.nlm.nih.gov/pubmed/33110073
http://dx.doi.org/10.1038/s41467-020-19193-y