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Silencing of sinusoidal DDR1 reduces murine liver metastasis by colon carcinoma

Liver metastasis depends on the collagenous microenvironment generated by hepatic sinusoidal cells (SCs). DDR1 is an atypical collagen receptor linked to tumor progression, but whether SCs express DDR1 and its implication in liver metastasis remain unknown. Freshly isolated hepatic stellate cells (H...

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Detalles Bibliográficos
Autores principales: Romayor, Irene, Badiola, Iker, Benedicto, Aitor, Márquez, Joana, Herrero, Alba, Arteta, Beatriz, Olaso, Elvira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591579/
https://www.ncbi.nlm.nih.gov/pubmed/33110221
http://dx.doi.org/10.1038/s41598-020-75395-w