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Characteristics of TCR Repertoire Associated With Successful Immune Checkpoint Therapy Responses

Immunotherapies have revolutionized cancer treatment. In particular, immune checkpoint therapy (ICT) leads to durable responses in some patients with some cancers. However, the majority of treated patients do not respond. Understanding immune mechanisms that underlie responsiveness to ICT will help...

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Detalles Bibliográficos
Autores principales: Kidman, Joel, Principe, Nicola, Watson, Mark, Lassmann, Timo, Holt, Robert A., Nowak, Anna K., Lesterhuis, Willem Joost, Lake, Richard A., Chee, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591700/
https://www.ncbi.nlm.nih.gov/pubmed/33163002
http://dx.doi.org/10.3389/fimmu.2020.587014