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Differential involvement of caspase-6 in amyloid-β-induced fragmentation of lamin A and B
Amyloid-β (Aβ), a peptide implicated in Alzheimer's disease, was shown to cause specific fragmentation of lamin proteins, which was mediated by an unidentified protease named nuclear scaffold protease (NSP) independently of caspase-6. Because caspase-6 is responsible for the fragmentation proce...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591731/ https://www.ncbi.nlm.nih.gov/pubmed/33145443 http://dx.doi.org/10.1016/j.bbrep.2020.100839 |