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Electrochemical, spectroscopic, and molecular docking studies of the interaction between the anti-retroviral drug indinavir and dsDNA

In this study, an electrochemical DNA biosensor was developed using a straightforward methodology to investigate the interaction of indinavir with calf thymus double-stranded deoxyribonucleic acid (ct-dsDNA) for the first time. The decrease in the oxidation signals of deoxyguanosine (dGuo) and deoxy...

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Detalles Bibliográficos
Autores principales: Mollarasouli, Fariba, Dogan-Topal, Burcu, Caglayan, Mehmet Gokhan, Taskin-Tok, Tugba, Ozkan, Sibel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591812/
https://www.ncbi.nlm.nih.gov/pubmed/33133731
http://dx.doi.org/10.1016/j.jpha.2020.08.004