Memantine, Simvastatin, and Epicatechin Inhibit 7-Ketocholesterol-induced Apoptosis in Retinal Pigment Epithelial Cells But Not Neurosensory Retinal Cells In Vitro

PURPOSE: 7-ketocholesterol (7kCh), a natural byproduct of oxidation in lipoprotein deposits is implicated in the pathogenesis of diabetic retinopathy and age-related macular degeneration (AMD). This study was performed to investigate whether several clinical drugs can inhibit 7kCh-induced caspase ac...

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Detalles Bibliográficos
Autores principales: Neekhra, Aneesh, Tran, Julia, Esfahani, Parsa R., Schneider, Kevin, Pham, Khoa, Sharma, Ashish, Chwa, Marilyn, Luthra, Saurabh, Gramajo, Ana L., Mansoor, Saffar, Kuppermann, Baruch D., Kenney, M. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PUBLISHED BY KNOWLEDGE E 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591846/
https://www.ncbi.nlm.nih.gov/pubmed/33133437
http://dx.doi.org/10.18502/jovr.v15i4.7781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591846/
https://www.ncbi.nlm.nih.gov/pubmed/33133437
http://dx.doi.org/10.18502/jovr.v15i4.7781

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