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E2F7−EZH2 axis regulates PTEN/AKT/mTOR signalling and glioblastoma progression

BACKGROUND: E2F transcription factors are considered to be important drivers of tumour growth. E2F7 is an atypical E2F factor, and its role in glioblastoma remains undefined. METHODS: E2F7 expression was examined in patients by IHC and qRT-PCR. The overall survival probability was determined by stat...

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Detalles Bibliográficos
Autores principales: Yang, Rui, Wang, Mei, Zhang, Guanghui, Bao, Yonghua, Wu, Yanan, Li, Xiuxiu, Yang, Wancai, Cui, Hongjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591888/
https://www.ncbi.nlm.nih.gov/pubmed/32814835
http://dx.doi.org/10.1038/s41416-020-01032-y