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Force-clamp spectroscopy identifies a catch bond mechanism in a Gram-positive pathogen

Physical forces have profound effects on cellular behavior, physiology, and disease. Perhaps the most intruiguing and fascinating example is the formation of catch-bonds that strengthen cellular adhesion under shear stresses. Today mannose-binding by the Escherichia coli FimH adhesin remains one of...

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Detalles Bibliográficos
Autores principales: Mathelié-Guinlet, Marion, Viela, Felipe, Pietrocola, Giampiero, Speziale, Pietro, Alsteens, David, Dufrêne, Yves F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591895/
https://www.ncbi.nlm.nih.gov/pubmed/33110079
http://dx.doi.org/10.1038/s41467-020-19216-8