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Spatiotemporal identification of druggable binding sites using deep learning
Identification of novel protein binding sites expands druggable genome and opens new opportunities for drug discovery. Generally, presence or absence of a binding site depends on the three-dimensional conformation of a protein, making binding site identification resemble the object detection problem...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591901/ https://www.ncbi.nlm.nih.gov/pubmed/33110179 http://dx.doi.org/10.1038/s42003-020-01350-0 |