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A pilot clinical study of the therapeutic antibody against canine PD-1 for advanced spontaneous cancers in dogs
Inhibition of programmed death 1 (PD-1), expressed on activated T cells, can break through immune resistance and elicit durable responses in human melanoma as well as other types of cancers. Canine oral malignant melanoma is one of the most aggressive tumors bearing poor prognosis due to its high me...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591904/ https://www.ncbi.nlm.nih.gov/pubmed/33110170 http://dx.doi.org/10.1038/s41598-020-75533-4 |