NKCC-1 mediated Cl(−) uptake in immature CA3 pyramidal neurons is sufficient to compensate phasic GABAergic inputs

Activation of GABA(A) receptors causes in immature neurons a functionally relevant decrease in the intracellular Cl(−) concentration ([Cl(−)](i)), a process termed ionic plasticity. Amount and duration of ionic plasticity depends on kinetic properties of [Cl(−)](i) homeostasis. In order to character...

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Detalles Bibliográficos
Autores principales: Kolbaev, Sergey N., Mohapatra, Namrata, Chen, Rongqing, Lombardi, Aniello, Staiger, Jochen F., Luhmann, Heiko J., Jedlicka, Peter, Kilb, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591924/
https://www.ncbi.nlm.nih.gov/pubmed/33110147
http://dx.doi.org/10.1038/s41598-020-75382-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591924/
https://www.ncbi.nlm.nih.gov/pubmed/33110147
http://dx.doi.org/10.1038/s41598-020-75382-1

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