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p53-R273H promotes cancer cell migration via upregulation of neuraminidase-1

Accumulating evidence indicates that hotspot p53 mutants have gain-of-function in promoting cell migration and tumor metastasis. However, the molecular mechanisms are not completely understood. Here, we show that a hotspot mutation, p53-R273H, promotes non-small cell lung cancer (NSCLC) cell migrati...

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Detalles Bibliográficos
Autores principales: Lv, Tao, Lv, Hong, Fei, Junjie, Xie, Yajun, Lian, Daqing, Hu, Jiang, Tang, Lizhou, Shi, Xiaodong, Wang, Jianling, Zhang, Shibo, Li, Fengtian, Jiang, Xianjie, Yi, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7591995/
https://www.ncbi.nlm.nih.gov/pubmed/33123278
http://dx.doi.org/10.7150/jca.44718