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Genetic Fine Mapping and Genomic Annotation Defines Causal Mechanisms at A Novel Colorectal Cancer Susceptibility Locus in Han Chinese

Genome-wide association studies of colorectal cancer (CRC) have identified two risk SNPs. The characterization of these risk regions in diverse racial groups with different linkage disequilibrium structure would aid in localizing the causal variants. Herein, fine mapping of the established CRC loci...

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Detalles Bibliográficos
Autores principales: Jiang, Kewei, Du, Fengying, lv, Liang, Zhuo, Hongqing, Xu, Tao, Peng, Lipan, Chen, Yuezhi, Li, Leping, Zhang, Jizhun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592009/
https://www.ncbi.nlm.nih.gov/pubmed/33123275
http://dx.doi.org/10.7150/jca.47189